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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3cf8f5c42b3a476fb63eb4048b5c6d0d41bbe382f218f8734c31fdc5ec82367' 
  AND token = '8IYMroRt3GYNgn89WYcTZ4A89nnQMuvzFDo2MqRZg2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}