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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b73074de37ba026d83b8e2fcee1b8b7f47436a89b4cc109b114f5fefce9e2ac9' 
  AND token = '6cTUN4bL4zluWszyW8AiUKswaTwqgROdUciDBP3IK8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}