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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e574fe4ec3e15aa497f8933d21a53c6b5c30ce01285bdb48ce1a8604c813b430' 
  AND token = 'ExIIyMWRxoUwBTTsZi/X464ni9WTIR6TR05TX32cwmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}