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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a67d0adfd2e7e6f380a8314284f79a1ed4247c72bced5dbbe7252eda5cc60885' 
  AND token = 'ra5KzFi6q+YlEWg5Z5Em0GGjEwQH/v42kW+Rkl5DKeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}