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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1216e7227708737261616e707996d70e9de3976a50f218a2c0f834862f55d5d4' 
  AND token = '/TrXDYHUEpM9ETvRKsHTQljZF1SG6AgMiq4s8smm/xA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}