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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b0c1da6ce710102fe5729db13c420c667c6f5085a2e0db425b9faab6e4e289f' 
  AND token = 'oqTyT1ves3GHmJ7b85DBtOYCAMUhb/OlVAw0oAHPKrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}