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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c99fb5168e805f7d27e4d7932b48af6daa7917fb2bf703dfec0a1e09765a3274' 
  AND token = '2vOn7Ki+F2LKf1LAELnVOMtpNeDph5qNM04hDffm4kE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}