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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea6c0d644986d48d6be277f3febed59f0d6bb3b139070c163252475bd2fab0d6' 
  AND token = '+BIevzH8RP1mYljwf7aO+78UHWdems9pUgD6pyT4/B4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}