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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44725cbd1f8374d84a247248c0c1982004f2eef1cdc7942d270e39f77f22c55b' 
  AND token = 'R/nNDr2Hb4VqpqwHE60Ro2paCOK7Q8tifW88OTqIYNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}