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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e563db1a8f1d43c699b0197afc8ced70db0b0ca4dee61c4c4c6b69ed1fcfd47b' 
  AND token = 'My+IJE2HSc+hHq6sEyztuicnbLNKN3nKKr2KCb/nYKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}