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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d2bc244ae3f4783d9afcd52c1c229061396c28f6d7aa14fac61f1cd4f4987c' 
  AND token = 'XlfO1Yl6ntY9V7XBEZrnhYGkR8hAMRb0kj1b2lrLaso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}