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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c844d5bc45f70e5e159016ee691875858012c4be1c30f06731bc6ed65dfab04' 
  AND token = 'lE08/Zg9ytx8hfj1XWINBbSYnpXoPhnRlQzQIoO4Qy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}