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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b1f5afc7e7e5387a07c7a94a342db8580b10f11f5203b3a57df586a2f9d401' 
  AND token = '1Z++K4rHbvTe816qaNhOEnRTUijKEDZ/4nSVN91ikaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}