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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21aea9f1dda314c37f6d0b14edb951d89d10d4a8cab85b4da603c16566c6f5a4' 
  AND token = 'MwWIOp3ONv0SarmP1rvEmGWQ2/4lpl8o6JZeUhvFqpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}