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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a50f72d3b5fcf04bb6923e0232771aad314fba01acfcf74f437a9be8d5f195d9' 
  AND token = 'aRD/PZ3LMtLUIom2xT7h/HpIT8lcHj1W2S13F1EEOOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}