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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb253244a574de67d6d7e9992c4da33cb2548e78ead094c7b4a2168932973b7c' 
  AND token = 'VkfC5GHYdoFejwNf1pHeCpPPEixnJ/6plb8tYmYRtlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}