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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5c06f6584cdb199f13a0d9a72c3e3e4a51999be8519d227824360ec98c91342' 
  AND token = 'Ezm9XpuHHpB0OWl9Tciagzr4h5TE8I2uULbuG1jXI38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}