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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c648c9f3394856e6216527740b2bfc9607e30859999a772b3c8076d1ca3e792' 
  AND token = 'SbpSfNYbEQTlLlYvqummscR7OACKorHLuTSx2BLDMQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}