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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e44c1c33c740b9ebf900897964794b02c09e843e368d4a006ff7d82796579dc8' 
  AND token = 'FkbdOXn/Yq1igaBr89hYWc9K+mMiK9Z+RmsgCZDX7yA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}