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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218689049aae96f1aa2b968bab3fb3aa48049d54eb676870e014d5db0482a0be' 
  AND token = 'zpTfd8uInvBxJvlrEP9BMlZ2auBL7LEUSBYiylN0vOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}