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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105eec65159887665fd781e2e31f2373c79ff1a66e292be8c200b3894a42c0fe' 
  AND token = 'JpOUJWEl3dl+znaEqxNXumKLPXW8Z+L1cMX7Xn4tVaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}