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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225fc1b5ecd72fa6ef9061f4a656c85cd8d7451d76cc05292437e09422d5b088' 
  AND token = 'TIUDwbmXX2t8J9kmZQGMAIcOQ1mL54y9pGbWPT6JfOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}