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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c8e9d9b88ebe48d23c49db29362e401b13abbb20e65c861b3c51d5a516588b' 
  AND token = '+5mTe4OgMKvRS+RubblYERhR0YM7GYVoF5N7VE80m4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}