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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100730cfda7c104bc354dbc0f6c96f4f8a5a6772b365cda32fdd669c2e86dc09' 
  AND token = 'y2y9NClLNnP7tqS78TRn9R34ARPr720G9kgXeRCBBpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}