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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45cb43030e1ccf2463b4b598f757de751ce0810a3d25f26637098bf697da37b1' 
  AND token = 'ppvPpNb0TDHO7pg/XuBkUeDN+vH+2FcClgeiiqzr14Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}