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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4c374012fb76a8406e241b15a9422cc2456e26f6befb4624a4c683048fb53db' 
  AND token = 'O0yczrhi5LlENkoH/p6vFa01ONHUN4+hlD+OpxFYmFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}