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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48863238e4cf111ecc7d11d50dc92af1db5d6480ff63b3fc7305586de4ff52ac' 
  AND token = 'Ka70eM3yNNk2ycqKx2qW/iqgcwF0pU8J1FEcQiu8Wzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}