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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1ed7c825c2e16f85255acb21d69e255385a007321df9f6583a4ee4fa21c2c3c' 
  AND token = 'ULwdWZZog4/33AM/p2aHGaWdmQLdequ2rTUsmmit6Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}