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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943e547f35587ee17994823115eb2ff5a4d2b4627c81f15f4d757420732a486f' 
  AND token = '2M+iaIAnAKlqAQxIOTxqkbO8u/E9V2j/2iofXoXy1H0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}