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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b21e26e689b798aa1cff9c48fd07f9ee674d1347fc2313ffb99d45da964b99e' 
  AND token = 'VG52LTTwj/zNYmDAWxhgWGRyMScXctOpaMGLE/7bO1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}