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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4322c7a0d2f60610725445e26a1e544c7b42817a281f4b930be3e757863b4285' 
  AND token = 'K3N9IquMrBU6TEGvoroX7rR0HgYNfmcNiYM4tV3wCsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}