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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '926e69aa22950aaf6995cd2eb08ed245509c99788c36dd17f1a510c35f5a2721' 
  AND token = 'ykuaWyBqqRhl45uVEu+DpwlZplUZ0T5O5YEA1xk1TsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}