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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163b1900b1729ab273d91c20cf1c841405fa6fc91f79518a9c505242874bb2d8' 
  AND token = 'BRKX2xsKVr0GE5n0/4QdO4Wc3n8VjR/0QXjcr9576kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}