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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '563a5d75fb92bd33230d6454f6c4502cc6db9bfad6ccf4ac33e7f0327838b3fd' 
  AND token = 'eA5MKOyEdfUNOtDvkiT+7ve2jQXsp/k8oWHO0wu0ooI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}