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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c8f1f78cf2e0c269d6a9e1047ef9f00c596aed1dc8e38e0be9e586853bb0452' 
  AND token = 'p6ADAevqmzEBX2BAIK94lkS8sRmmnJhB5bIxrADcPKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}