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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100eb72b6a1054e5781d88a73bde0f55f04126f2bf5b521b37be55fd5fcb81a8' 
  AND token = 'jGx5BMeY7MTQbxGx+Mp4swBqaGs/ugjpwbIkhbp0vdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}