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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d4963875f996a39113918f9a54c97a5b2bc91b2d133314a4b38b5b576805b42' 
  AND token = 'uG3ZQRd4YRSNpBp+9v2Yvsz22JDWA2CPm+1uLxl2YDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}