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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64dfd1de4ad1a241972a0e6b240024b00815b303f958c23000948a36adfa46ad' 
  AND token = 'QcJXQ9YqVk3ctVy3f4YPvRg6ooIndpWJp9jgzHXUWJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}