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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fc19007bf5edb7176e44ef36f237fb94d42c88979c36d1d3a6783da6b22af7f' 
  AND token = '1I9b044DxWX381kquho0CaAM5RyZBH0q0lj9Jzj0t9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}