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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43dd968c67e2480958da212b3dfba8bf369aebcdb69bffc81e5dab6d43da3b38' 
  AND token = 'Ed5p8v+Iu4U7zkEUefD+SojJqQiaa1Mp5/Yc42G49hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}