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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c78a19601a09c50a6be4d540543634b25902a827187b30ee7f5cb660b3b358' 
  AND token = 'NIzx16c9sUe6wC0oRIgi++jwbc9R2OBDBnXo6x8xOIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}