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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efaf258aa81025fc9b6dd619735a5706c2f11bad2bdf86859e1ef19a15842629' 
  AND token = 'z16EAe7B1tL6ne7EL9wSunaNxj2UTUXeV4Kknp/Q03Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}