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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5418003d6c342940c196cf4937db81ccf88d40663156d44e904103a80f6e44ad' 
  AND token = 'JW8e7VogsnQRrSaYpV17bnyFS9TpnmGx/LI+0hZT3Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}