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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743bff73a54bc735b03a6b5f8795d54d59358284a385546ee396ad9fd8fb6961' 
  AND token = 'juQTzFUOMkI8JAS26INxA823riNvXCXwa73qKmDe8Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}