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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bd5be3befbba50a0fd5521d98f7490e02b23c2d47b1b3b3dabf01a8b3aeca45' 
  AND token = '8FweoA4kL+qOnxq+nl6/IC0M/ZqYTL4kpRfm+RspvwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}