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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9a9399af4051bd82024d5f538d154d6d8e93f962628432cfccc11b9826028a6' 
  AND token = 'IuDrK0a2UUFhLPN1PJprJrxjUdofE4kujnv3kGcupUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}