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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1050d8c8fbb9529795f33c6941d6572876e5394d72c24c623d9af8ef17245e4a' 
  AND token = 'vwXWL8/b0v9aeDMW85PHtjrrYaZj5CMlniH/YLbQpkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}