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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca3f721747c4b6950f85f4c129101ac9f7f785757e594c385706f6cd989afd5' 
  AND token = 'am4e938L7tEbQ68V03pZxzvQbyDXLwdJOxNW21OJZhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}