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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452fa35027a334d48e0e4c7997bfede8e6369736b729bbdbc73fb5226857cd9f' 
  AND token = '68yyoKcMSDQ2ZgLGUcWjQG4QJ51q9sCQIYxIEV1DCpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}