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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de41ceb5054c35a0a021814eb8ad7f0da4f9063cadcaaf53424e963b4cc091ea' 
  AND token = '/lHL27lQf/9RjmJMeHpyqfXisA7n56RqISdi0Hq2U2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}